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A surveillance case definition is a set of uniform criteria used to define a disease for public health surveillance. Surveillance case definitions enable public health officials to classify and count cases consistently across reporting jurisdictions. Surveillance case definitions are not intended to be used by healthcare providers for making a clinical diagnosis or determining how to meet an individual patient’s health needs.

While the list of reportable conditions varies by state, the Council of State and Territorial Epidemiologists (CSTE) has recommended that state health departments report cases of selected diseases to CDC’s National Notifiable Diseases Surveillance System (NNDSS).  Every year, case definitions are updated using CSTE’s Position Statements.  They provide uniform criteria of national notifiable infectious and non-infectious conditions for reporting purposes.

Use the search box below to search for notifiable diseases case definitions by name or year.

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Notifiable Condition Lists

A

Acanthamoeba disease (excluding keratitis)

Acanthamoeba keratitis

Acquired immunodeficiency syndrome

Acute Flaccid Myelitis (AFM)

AFM

AIDS

AIDS/HIV

Alpha-gal Syndrome

Amebiasis

Anaplasma phagocytophilum

Anaplasma phagocytophilum infection

Anaplasmosis

Anthrax

Arboviral diseases, neuroinvasive and non-neuroinvasive

Arboviral encephalitis

Arboviral encephalitis or meningitis

B

Babesiosis

Balamuthia mandrillaris disease

Blastomycosis

Botulism

Botulism, foodborne

Botulism, infant

Botulism, other

Botulism, wound

Brucellosis

C

California serogroup encephalitis

California serogroup encephalitis/meningitis

California serogroup virus diseases

Campylobacteriosis

Cancer

Candida auris

Candida auris, clinical

Candida auris, colonization/screening

Candida auris, screening

Candida auris, screening/surveillance

Carbapenemase Producing Carbapenem-Resistant Enterobacteriaceae (CP-CRE)

Carbapenemase-Producing Organisms (CPO)

Carbapenemase-producing organisms, clinical

Carbapenemase-producing organisms, screening

Carbon monoxide poisoning

Chancroid

Chickenpox

Chikungunya virus disease

Chlamydia trachomatis infection

Chlamydia trachomatis, genital infections

Cholera

Coccidioidomycosis

Congenital Cytomegalovirus (cCMV) Infection and Disease

Congenital cytomegalovirus disease

Congenital cytomegalovirus infection

Congenital syphilis

Congenital Toxoplasmosis

Coronavirus Disease 2019 (COVID-19)

CP-CRE, Enterobacter spp.

CP-CRE, Escherichia coli (E. coli)

CP-CRE, Klebsiella spp.

Crimean-Congo hemorrhagic fever virus

CRS

Cryptococcus gattii infection

Cryptosporidiosis

Cyclosporiasis

D

Dengue

Dengue fever

Dengue hemorrhagic fever

Dengue shock syndrome

Dengue virus infections

Dengue-like illness

DF

DHF

Diphtheria

DRSP

DSS

E

E. coli O157:H7

Eastern equine encephalitis

Eastern equine encephalitis virus disease

Eastern equine encephalitis/meningitis

Ebola virus

EHEC

Ehrlichia chaffeensis

Ehrlichia chaffeensis infection

Ehrlichia ewingii

Ehrlichia ewingii infection

Ehrlichia muris eauclairensis

Ehrlichia, other spp. or unspeciated

Ehrlichiosis

Ehrlichiosis and anaplasmosis

Encephalitis

Encephalitis, arboviral

Encephalitis, postinfectious (or parainfectious)

Encephalitis, primary

Enterohemorrhagic Escherichia coli

Escherichia coli O157:H7

F

Foodborne Disease Outbreak

Free-living amebae infections

G

GAS

Genital herpes

Genital warts

German measles

Giardiasis

Gonorrhea

Granuloma inguinale

H

Haemophilus influenzae, invasive disease

Hansen's disease

Hantavirus infection, non-Hantavirus pulmonary syndrome

Hantavirus pulmonary syndrome

Hemolytic uremic syndrome, post-diarrheal

Hepatitis A, acute

Hepatitis B, acute

Hepatitis B, acute (historical version)

Hepatitis B, acute and chronic

Hepatitis B, chronic

Hepatitis B, chronic (historical version)

Hepatitis B, perinatal infection

Hepatitis C, acute

Hepatitis C, chronic

Hepatitis C, Perinatal Infection

Hepatitis, viral, acute

HGE

Histoplasmosis

HIV infection (AIDS has been reclassified as HIV Stage III)

HME

HPS

Human granulocytic ehrlichiosis

Human monocytic ehrlichiosis

HUS

I

Influenza-associated hospitalizations

Influenza-associated pediatric mortality

Invasive Cronobacter infection Among Infants

Invasive pneumococcal disease

IPD

K

Kawasaki syndrome

L

Lassa virus

Latent TB Infection (TB Infection)

Lead in Blood

Lead, elevated blood levels

Lead, elevated blood levels, adult (≥16 Years)

Lead, elevated blood levels, children (<16 Years)

Legionellosis

Leprosy

Leptospirosis

Listeriosis

Lujo virus

Lyme disease

Lymphogranuloma venereum

M

Malaria

Marburg virus

Measles

Melioidosis

Meningitis, aseptic

Meningitis, other bacterial

Meningococcal disease

MIS-C

MPC

Mpox virus infection

Mucopurulent cervicitis

Multisystem inflammatory syndrome in children (MIS-C) associated with SARS-CoV-2 infection

Mumps

N

Naegleria fowleri causing primary amebic meningoencephalitis (PAM)

Neurosyphilis

New World arenavirus - Chapare virus

New World arenavirus – Guanarito virus

New World arenavirus – Junin virus

New World arenavirus – Machupo virus

New World arenavirus – Sabia virus

NGU

Nongonococcal urethritis

Novel influenza A virus infections

O

Ornithosis

Other or unspecified human ehrlichiosis

P

Pelvic inflammatory disease

Pertussis

Pesticide-related illness and injury, acute

PID

Plague

Poliomyelitis, paralytic

Poliovirus infection, nonparalytic

Poliovirus, Nonparalytic Poliovirus Infection

Poliovirus, Paralytic Poliomyelitis

Poliovirus, Paralytic Poliomyelitis and Nonparalytic Poliovirus Infection

Powassan encephalitis/meningitis

Powassan virus disease

Psittacosis

Q

Q fever

Q fever, acute

Q fever, chronic

R

Rabies, animal

Rabies, human

Respiratory Syncytial Virus-Associated Mortality (RSV-Associated Mortality)

Reye syndrome

Rheumatic fever

RMSF

Rocky Mountain spotted fever

Rubella

Rubella, congenital syndrome

Rubeola

S

Salmonella Paratyphi infection (Salmonella enterica serotypes Paratyphi A, B [tartrate negative], and C [S. Paratyphi])

Salmonella Typhi infection (Salmonella enterica serotype Typhi)

Salmonellosis

SARS-CoV

Severe acute respiratory syndrome-associated coronavirus disease

Severe dengue

Shiga toxin-producing Escherichia coli

Shigellosis

Silicosis

Smallpox

Spinal cord injury

Spotted fever rickettsiosis

St. Louis encephalitis

St. Louis encephalitis virus disease

St. Louis encephalitis/meningitis

STEC

Streptococcal toxic shock syndrome

Streptococcus disease, invasive, Group A

Streptococcus pneumoniae, drug-resistant invasive disease, drug-resistant invasive disease

Streptococcus pneumoniae, invasive disease

Streptococcus pneumoniae, invasive disease (child, <5 years)

Streptococcus pneumoniae, invasive disease non-drug resistant (child, <5 years)

Strongyloidiasis

STSS

Syphilis

Syphilis, Congenital

Syphilis, early latent

Syphilis, early non-primary non-secondary

Syphilis, late latent

Syphilis, late with clinical manifestations (including late benign syphilis and cardiovascular syphilis)

Syphilis, late, with clinical manifestations other than neurosyphilis

Syphilis, latent

Syphilis, latent unknown duration

Syphilis, primary

Syphilis, secondary

Syphilis, unknown duration or late

Syphilitic stillbirth

T

TB

Tetanus

Toxic shock syndrome (other than streptococcal)

Toxoplasma gondii

Toxoplasmosis

Toxoplasmosis, Active- Primary Infection

Toxoplasmosis, Active- Reactivation Disease

Toxoplasmosis, Past Infection/Unable to Classify

Trichinellosis

Trichinosis

TSS

Tuberculosis

Tularemia

Typhoid fever

U

Undetermined human ehrlichiosis/anaplasmosis

V

Valley fever

Vancomycin-intermediate Staphylococcus aureus and Vancomycin-resistant Staphylococcus Aureus

Varicella

Varicella deaths

Variola

VHF

Vibriosis

Viral hemorrhagic fever

Viral meningitis

VISA/VRSA

W

Waterborne Disease Outbreak

West Nile encephalitis/meningitis

West Nile virus disease

Western equine encephalitis

Western equine encephalitis virus disease

Western equine encephalitis/meningitis

Whooping cough

Y

Yellow fever

Z

Zika virus disease and Zika virus infection

Zika virus disease, congenital

Zika virus disease, non-congenital

Zika virus infection, congenital

Zika virus infection, non-congenital