| Acanthamoeba disease (excluding keratitis) |
|
|
|
- |
- |
| Acanthamoeba keratitis |
|
|
|
- |
- |
| Acquired immunodeficiency syndrome |
AIDS |
|
|
2000 |
2008 |
| Acute Flaccid Myelitis (AFM) |
AFM |
|
|
- |
- |
| Alpha-gal Syndrome (AGS) |
|
|
|
- |
- |
| Amebiasis |
|
|
Entamoeba histolytica |
1933 |
1994 |
| Anaplasma phagocytophilum |
|
|
|
2024 |
Current |
| Anaplasma phagocytophilum infection |
|
|
|
2008 |
2023 |
| Anaplasmosis |
|
|
|
2024 |
Current |
| Anthrax |
|
|
Bacillus anthracis |
1944 |
Current |
| Arboviral diseases, neuroinvasive and non-neuroinvasive |
|
|
|
2005 |
Current |
| Arboviral encephalitis |
|
|
|
1995 |
2001 |
| Arboviral encephalitis or meningitis |
|
|
|
2002 |
2003 |
| Babesiosis |
|
|
Babesia spp. |
2011 |
Current |
| Balamuthia mandrillaris disease |
|
|
|
- |
- |
| Blastomycosis |
|
|
|
- |
- |
| Botulism |
|
|
Clostridium botulinum |
1947 |
Current |
| Botulism, foodborne |
|
|
|
1983 |
Current |
| Botulism, infant |
|
|
|
1983 |
Current |
| Botulism, other |
|
|
|
1983 |
Current |
| Botulism, wound |
|
|
|
1983 |
Current |
| Brucellosis |
|
|
Brucella spp. |
1944 |
Current |
| California serogroup encephalitis |
|
|
|
1995 |
2001 |
| California serogroup encephalitis/meningitis |
|
|
|
2002 |
2003 |
| California serogroup virus diseases |
|
|
|
2005 |
Current |
| Campylobacteriosis |
|
|
Campylobacter spp. |
2015 |
Current |
| Cancer |
|
|
|
2010 |
Current |
| Candida auris |
|
|
|
- |
- |
| Candida auris, clinical |
|
|
|
2019 |
Current |
| Candida auris, colonization/screening |
|
|
|
- |
- |
| Candida auris, screening |
|
|
|
2023 |
Current |
| Candida auris, screening/surveillance |
|
|
|
- |
- |
| Carbapenemase Producing Carbapenem-Resistant Enterobacteriaceae (CP-CRE) |
|
|
|
2018 |
2022 |
| Carbapenemase-Producing Organisms (CPO) |
|
|
|
2023 |
Current |
| Carbapenemase-producing organisms, clinical |
|
|
|
2023 |
Current |
| Carbapenemase-producing organisms, screening |
|
|
|
2023 |
Current |
| Carbon monoxide poisoning |
|
|
|
2014 |
Current |
| Chagas disease |
|
Chagas Disease |
|
- |
- |
| Chagas disease, acute |
|
|
|
- |
- |
| Chagas disease, chronic |
|
|
|
- |
- |
| Chagas disease, congenital |
|
|
|
- |
- |
| Chancroid |
|
|
Haemophilus ducreyi |
1944 |
Current |
| Chikungunya virus disease |
|
|
|
2015 |
Current |
| Chlamydia trachomatis infection |
|
|
|
2010 |
Current |
| Chlamydia trachomatis, genital infections |
|
|
|
1995 |
2009 |
| Cholera |
|
|
Vibrio cholerae O1/O139 |
1944 |
Current |
| Coccidioidomycosis |
|
Valley fever |
Coccidioides spp. |
2011 |
Current |
| Coccidioidomycosis |
|
Valley fever |
Coccidioides spp. |
1995 |
2009 |
| Congenital Cytomegalovirus (cCMV) Infection and Disease |
|
|
|
- |
- |
| Congenital cytomegalovirus disease |
|
|
|
- |
- |
| Congenital cytomegalovirus infection |
|
|
|
- |
- |
| Congenital Oropouche Virus Disease |
|
|
|
2025 |
Current |
| Congenital syphilis |
|
|
Treponema pallidum |
2015 |
Current |
| Congenital Toxoplasmosis |
|
|
|
- |
- |
| Congenital Zika Virus Disease |
|
|
|
2024 |
Current |
| Coronavirus Disease 2019 (COVID-19) |
|
|
|
2020 |
2024 |
| CP-CRE, Enterobacter spp. |
|
|
|
2018 |
2022 |
| CP-CRE, Escherichia coli (E. coli) |
|
|
|
2018 |
2022 |
| CP-CRE, Klebsiella spp. |
|
|
|
2018 |
2022 |
| Crimean-Congo hemorrhagic fever virus |
|
|
|
2010 |
Current |
| Cryptococcus gattii infection |
|
|
C. gattii |
- |
- |
| Cryptosporidiosis |
|
|
Cryptosporidium spp. |
1995 |
Current |
| Cutaneous anthrax |
|
|
|
- |
- |
| Cyclosporiasis |
|
|
Cyclospora cayetanensis |
1999 |
Current |
| Dengue |
|
|
|
2015 |
Current |
| Dengue fever |
DF |
|
|
2010 |
2014 |
| Dengue hemorrhagic fever |
DHF |
|
|
2010 |
2014 |
| Dengue shock syndrome |
DSS |
|
|
2010 |
2014 |
| Dengue virus infections |
|
|
|
2010 |
Current |
| Dengue-like illness |
|
|
|
2015 |
Current |
| Diphtheria |
|
|
Corynebacterium diphtheriae |
1944 |
Current |
| Eastern equine encephalitis |
|
|
|
1995 |
2001 |
| Eastern equine encephalitis virus disease |
|
|
|
2005 |
Current |
| Eastern equine encephalitis/meningitis |
|
|
|
2002 |
2003 |
| Ebola virus |
|
|
|
2010 |
Current |
| Ehrlichia chaffeensis |
|
|
|
2024 |
Current |
| Ehrlichia chaffeensis infection |
|
|
|
2008 |
2023 |
| Ehrlichia ewingii |
|
|
|
2024 |
Current |
| Ehrlichia ewingii infection |
|
|
|
2008 |
2023 |
| Ehrlichia muris eauclairensis |
|
|
|
2024 |
Current |
| Ehrlichia, other spp. or unspeciated |
|
|
|
2024 |
Current |
| Ehrlichiosis |
|
|
|
1999 |
Current |
| Ehrlichiosis and anaplasmosis |
|
|
|
2008 |
2023 |
| Encephalitis |
|
|
|
1926 |
1994 |
| Encephalitis, arboviral |
|
|
|
- |
- |
| Encephalitis, postinfectious (or parainfectious) |
|
|
|
1964 |
1994 |
| Encephalitis, primary |
|
|
|
1926 |
1994 |
| Enterohemorrhagic Escherichia coli |
EHEC |
|
|
2001 |
2005 |
| Escherichia coli O157:H7 |
|
E. coli O157:H7 |
|
1995 |
2000 |
| Firearm-related injury |
|
|
|
- |
- |
| Foodborne Disease Outbreak |
|
|
|
2011 |
Current |
| Free-living amebae infections |
|
|
|
- |
- |
| Genital herpes |
|
|
Herpes Simplex Virus |
- |
- |
| Genital warts |
|
|
|
- |
- |
| Giardiasis |
|
|
|
2002 |
Current |
| Gonorrhea |
|
|
Neisseria gonorrhoeae |
1944 |
Current |
| Granuloma inguinale |
|
|
Calymmatobacterium granulomatis |
1942 |
1994 |
| Haemophilus Influenzae, Invasive disease |
|
|
|
1991 |
Current |
| Hantavirus infection, non-Hantavirus pulmonary syndrome |
|
|
|
2015 |
Current |
| Hantavirus pulmonary syndrome |
HPS |
|
|
1995 |
Current |
| Hemolytic uremic syndrome, post-diarrheal |
HUS |
|
|
1995 |
Current |
| Hepatitis A, acute |
|
|
|
1966 |
Current |
| Hepatitis B, acute |
|
|
|
2024 |
Current |
| Hepatitis B, acute (historical version) |
|
|
|
1966 |
2023 |
| Hepatitis B, acute and chronic |
|
|
|
2024 |
Current |
| Hepatitis B, chronic |
|
|
|
2024 |
Current |
| Hepatitis B, chronic (historical version) |
|
|
|
2003 |
2023 |
| Hepatitis B, perinatal infection |
|
|
|
2017 |
Current |
| Hepatitis B, perinatal virus infection |
|
|
|
1995 |
2016 |
| Hepatitis C, acute |
|
|
|
1994 |
Current |
| Hepatitis C, chronic |
|
|
|
2016 |
Current |
| Hepatitis C, chronic |
|
|
|
2010 |
2010 |
| Hepatitis C, past or present |
|
|
|
2011 |
2015 |
| Hepatitis C, past or present |
|
|
|
2003 |
2009 |
| Hepatitis C, perinatal infection |
|
|
|
2018 |
Current |
| Hepatitis D Virus |
|
|
|
- |
- |
| Hepatitis, viral, acute |
|
|
|
1947 |
1999 |
| Histoplasmosis |
|
|
|
- |
- |
| HIV infection (AIDS has been reclassified as HIV Stage III) |
AIDS/HIV |
|
|
2009 |
Current |
| Human granulocytic ehrlichiosis |
HGE |
|
Anaplasma phagocytophilum |
1999 |
2007 |
| Human monocytic ehrlichiosis |
HME |
|
Ehrlichia chaffeensis |
1999 |
2007 |
| Influenza-associated hospitalizations |
|
|
|
- |
- |
| Influenza-associated pediatric mortality |
|
|
|
2004 |
Current |
| Ingestion anthrax |
|
|
|
- |
- |
| Inhalation anthrax |
|
|
|
- |
- |
| Injection anthrax |
|
|
|
- |
- |
| Invasive Cronobacter infection Among Infants |
|
|
|
2024 |
Current |
| Invasive pneumococcal disease |
IPD |
Streptococcus pneumoniae, invasive disease |
Streptococcus pneumoniae |
2010 |
Current |
| Kawasaki syndrome |
|
|
|
- |
- |
| Lassa virus |
|
|
|
2010 |
Current |
| Latent TB Infection (TB Infection) |
|
|
Mycobacterium tuberculosis |
- |
- |
| Lead in Blood |
|
|
|
2010 |
Current |
| Lead, elevated blood levels |
|
|
|
2010 |
Current |
| Lead, elevated blood levels, adult (≥16 Years) |
|
|
|
2010 |
Current |
| Lead, elevated blood levels, children (<16 Years) |
|
|
|
2010 |
Current |
| Legionellosis |
|
|
Legionella pneumophila |
1976 |
Current |
| Leprosy (Hansen's Disease) |
|
Leprosy |
Mycobacterium leprae |
1970 |
Current |
| Leptospirosis |
|
|
Leptospira interrogans |
2014 |
Current |
| Leptospirosis |
|
|
Leptospira interrogans |
1947 |
1994 |
| Leptospirosis (Leptospira interrogans) |
|
|
Leptospira interrogans |
2014 |
Current |
| Listeriosis |
|
|
Listeria monocytogenes |
2000 |
Current |
| Lujo virus |
|
|
|
2011 |
Current |
| Lyme disease |
|
|
Borrelia burgdorferi |
1991 |
Current |
| Lymphogranuloma venereum |
|
|
Chlamydia trachomatis |
1941 |
1994 |
| Malaria |
|
|
Plasmodium spp. |
1944 |
Current |
| Marburg virus |
|
|
|
2010 |
Current |
| Measles |
|
Rubeola |
|
1944 |
Current |
| Melioidosis |
|
|
Burkholderia pseudomallei |
2023 |
Current |
| Melioidosis |
|
|
Burkholderia pseudomallei |
- |
- |
| Meningitis, aseptic |
|
Viral meningitis |
|
1960 |
1994 |
| Meningitis, other bacterial |
|
|
|
- |
- |
| Meningococcal disease |
|
|
Neisseria meningitidis |
1944 |
Current |
| Monkeypox virus infection |
|
|
|
2022 |
Current |
| Mucopurulent cervicitis |
MPC |
|
|
- |
- |
| Multisystem inflammatory syndrome in children (MIS-C) associated with SARS-CoV-2 infection |
MIS-C |
|
|
- |
- |
| Mumps |
|
|
|
1968 |
Current |
| Naegleria fowleri causing primary amebic meningoencephalitis (PAM) |
|
|
|
- |
- |
| Neurosyphilis |
|
|
|
1944 |
2013 |
| New World arenavirus - Chapare virus |
|
|
|
2022 |
Current |
| New World arenavirus – Guanarito virus |
|
|
|
2010 |
Current |
| New World arenavirus – Junin virus |
|
|
|
2010 |
Current |
| New World arenavirus – Machupo virus |
|
|
|
2010 |
Current |
| New World arenavirus – Sabia virus |
|
|
|
2010 |
Current |
| Non-congenital Oropouche Virus Disease |
|
|
|
2025 |
Current |
| Non-congenital Zika Virus Disease |
|
|
|
2024 |
Current |
| Non-pestis Yersiniosis |
|
|
|
- |
- |
| Nongonococcal urethritis |
NGU |
|
|
- |
- |
| Novel influenza A virus infections |
|
|
|
2007 |
Current |
| Oropouche Virus Disease |
OROV |
|
|
2025 |
Current |
| Other or unspecified human ehrlichiosis |
|
|
|
2001 |
2007 |
| Pelvic inflammatory disease |
PID |
|
|
- |
- |
| Pertussis |
|
Whooping cough |
Bordetella pertussis |
1973 |
Current |
| Pesticide-related illness and injury, acute |
|
|
|
2010 |
Current |
| Plague |
|
|
Yersinia pestis |
1944 |
Current |
| Poliomyelitis, paralytic |
|
|
|
1954 |
2023 |
| Poliovirus infection, nonparalytic |
|
|
|
2007 |
2023 |
| Poliovirus, Nonparalytic Poliovirus Infection |
|
|
|
2024 |
Current |
| Poliovirus, Paralytic Poliomyelitis |
|
|
|
2024 |
Current |
| Poliovirus, Paralytic Poliomyelitis and Nonparalytic Poliovirus Infection |
|
|
|
2024 |
Current |
| Powassan encephalitis/meningitis |
|
|
|
2002 |
2003 |
| Powassan virus disease |
|
|
|
2005 |
Current |
| Psittacosis |
|
Ornithosis |
Chlamydophila psittaci |
1944 |
Current |
| Q fever |
|
|
Coxiella burnetii |
2000 |
Current |
| Q fever, acute |
|
|
|
2008 |
Current |
| Q fever, chronic |
|
|
|
2008 |
Current |
| Rabies, animal |
|
|
|
1944 |
Current |
| Rabies, human |
|
|
|
1944 |
Current |
| Respiratory Syncytial Virus-Associated Mortality (RSV-Associated Mortality) |
|
|
|
- |
- |
| Reye syndrome |
|
|
|
- |
- |
| Rheumatic fever |
|
|
|
1956 |
1994 |
| Rift Valley fever virus |
|
|
|
2025 |
Current |
| Rocky Mountain spotted fever |
RMSF |
|
Rickettsia rickettsii |
1944 |
2009 |
| Rubella |
|
German measles |
|
1966 |
Current |
| Rubella, congenital syndrome |
CRS |
|
|
1966 |
Current |
| Salmonella Paratyphi infection (Salmonella enterica serotypes Paratyphi A, B [tartrate negative], and C [S. Paratyphi]) |
|
|
|
2019 |
Current |
| Salmonella Typhi infection (Salmonella enterica serotype Typhi) |
|
|
|
2019 |
Current |
| Salmonellosis |
|
|
Salmonella spp. |
1944 |
Current |
| Severe acute respiratory syndrome-associated coronavirus disease |
SARS-CoV |
|
|
2003 |
Current |
| Severe dengue |
|
|
|
2015 |
Current |
| Shiga toxin-producing Escherichia coli |
STEC |
|
|
2006 |
Current |
| Shigellosis |
|
|
Shigella spp. |
1944 |
Current |
| Silicosis |
|
|
|
2010 |
Current |
| Smallpox |
|
Variola |
|
2004 |
Current |
| Smallpox |
|
Variola |
|
1944 |
1988 |
| Spinal cord injury |
|
|
|
- |
- |
| Spotted fever rickettsiosis |
|
|
Rickettsia spp. |
2010 |
Current |
| St. Louis encephalitis |
|
|
|
1995 |
2001 |
| St. Louis encephalitis virus disease |
|
|
|
2005 |
Current |
| St. Louis encephalitis/meningitis |
|
|
|
2002 |
2003 |
| Streptococcal toxic shock syndrome |
STSS |
|
Streptococcus pyogenes |
1995 |
Current |
| Streptococcus disease, invasive, Group A |
GAS |
|
Streptococcus pyogenes |
1995 |
2009 |
| Streptococcus pneumoniae, drug-resistant invasive disease |
DRSP |
|
Streptococcus pneumoniae |
1995 |
2009 |
| Streptococcus pneumoniae, invasive disease (child, <5 years) |
|
|
Streptococcus pneumoniae |
2000 |
2006 |
| Streptococcus pneumoniae, invasive disease non-drug resistant (child, <5 years) |
|
|
Streptococcus pneumoniae |
2007 |
2009 |
| Strongyloidiasis |
|
|
|
- |
- |
| Syphilis |
|
|
Treponema pallidum |
1944 |
Current |
| Syphilis, congenital |
|
|
|
1989 |
2014 |
| Syphilis, Congenital |
|
|
|
1944 |
Current |
| Syphilis, early latent |
|
|
|
1944 |
2017 |
| Syphilis, early latent |
|
|
|
1944 |
2013 |
| Syphilis, early non-primary non-secondary |
|
|
|
1944 |
Current |
| Syphilis, late latent |
|
|
|
1944 |
2017 |
| Syphilis, late with clinical manifestations (including late benign syphilis and cardiovascular syphilis) |
|
|
|
2014 |
2017 |
| Syphilis, late, with clinical manifestations other than neurosyphilis |
|
|
|
1944 |
2013 |
| Syphilis, latent |
|
|
|
1944 |
2013 |
| Syphilis, latent unknown duration |
|
|
|
1944 |
2013 |
| Syphilis, primary |
|
|
|
1944 |
Current |
| Syphilis, secondary |
|
|
|
1944 |
Current |
| Syphilis, unknown duration or late |
|
|
|
1944 |
Current |
| Syphilitic stillbirth |
|
|
|
2015 |
Current |
| Syphilitic stillbirth |
|
|
|
1941 |
2014 |
| Syphilitic Stillbirth |
|
|
|
1941 |
Current |
| Tetanus |
|
|
Clostridium tetani |
1947 |
Current |
| Toxic shock syndrome (other than streptococcal) |
TSS |
|
|
1983 |
Current |
| Toxoplasma gondii |
|
|
|
- |
- |
| Toxoplasmosis |
|
|
|
- |
- |
| Toxoplasmosis, Active- Primary Infection |
|
|
|
- |
- |
| Toxoplasmosis, Active- Reactivation Disease |
|
|
|
- |
- |
| Toxoplasmosis, Past Infection/Unable to Classify |
|
|
|
- |
- |
| Trichinellosis |
|
Trichinosis |
Trichinella spp. |
1966 |
Current |
| Tuberculosis |
TB |
|
Mycobacterium tuberculosis |
1951 |
Current |
| Tularemia |
|
|
Francisella tularensis |
1927 |
Current |
| Typhoid fever |
|
|
Salmonella enterica serotype Typhi |
1944 |
2018 |
| Undetermined human ehrlichiosis/anaplasmosis |
|
|
|
2008 |
2023 |
| Vancomycin-intermediate Staphylococcus aureus and Vancomycin-resistant Staphylococcus aureus |
VISA/VRSA |
|
|
2004 |
Current |
| Vancomycin-intermediate Staphylococcus Aureus and Vancomycin-resistant Staphylococcus Aureus |
VISA/VRSA |
|
|
2004 |
Current |
| Varicella |
|
Chickenpox |
|
2003 |
Current |
| Varicella |
|
Chickenpox |
|
1972 |
1981 |
| Varicella deaths |
|
|
|
2002 |
Current |
| Vibriosis |
|
|
any species of the family Vibrionaceae, other than toxigenic Vibrio cholerae O1 or O139 |
2007 |
Current |
| Viral hemorrhagic fever |
VHF |
|
|
2010 |
Current |
| Waterborne Disease Outbreak |
|
|
|
2010 |
Current |
| Welder's anthrax |
|
|
|
- |
- |
| West Nile encephalitis/meningitis |
|
|
|
2002 |
2003 |
| West Nile virus disease |
|
|
|
2005 |
Current |
| Western equine encephalitis |
|
|
|
1995 |
2001 |
| Western equine encephalitis virus disease |
|
|
|
2005 |
Current |
| Western equine encephalitis/meningitis |
|
|
|
2002 |
2003 |
| Yellow fever |
|
|
|
1944 |
Current |
| Zika Virus Disease |
|
|
|
2024 |
Current |
| Zika virus disease and Zika virus infection |
|
|
|
2016 |
2023 |
| Zika virus disease, congenital |
|
|
|
2016 |
2023 |
| Zika virus disease, non-congenital |
|
|
|
2016 |
2023 |
| Zika virus disease, non-congenital infection |
|
|
|
2016 |
2016 |
| Zika virus disease, non-congenital infection and Zika virus, congenital infection |
|
|
|
2016 |
2016 |
| Zika virus infection, congenital |
|
|
|
2016 |
2023 |
| Zika virus infection, non-congenital |
|
|
|
2016 |
2023 |
| Zika virus, congenital infection |
|
|
|
2016 |
2016 |
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